Cambridge Dictionaries online Cambridge Dictionaries online

The most popular online dictionary and thesaurus for learners of English

  

lose your shirt

US informal

Definition

to lose a lot of money, especially as a result of a bet (= money risked when you guess the result of something)Profits and lossesGambling and bookmakingTaking risks
(Definition of lose your shirt from the Cambridge Advanced Learner's Dictionary & Thesaurus © Cambridge University Press)