B2[C or U]the fact that you no longer have something or have less of something: Many parents feel a sense of loss when their children leave home.He suffered a gradual loss of memory.There will be substantial job losses if the factory closes down.blood/hair/weight lossLosing and lossWinning and losingC2[S]a disadvantage caused by someone leaving or by something being taken away: It would be a great loss to the department if you left.Advantage and disadvantageB2[C or U]the death of a person: They never got over the loss of their son.Death and dyingC1[C]a situation in which a business spends more money than it earns: The company announced a pre-tax loss of three million pounds.AccountingProfits and lossesloss of life›an occasion when a number of people die: The plane crashed with serious loss of life.Death and dying