C2felt or experienced very strongly or in an extreme way: His mother's death when he was aged six had a very profound effect on him.The invention of the contraceptive pill brought about profound changes in the lives of women.Those two lines of poetry express perfectly the profound sadness of loss.My grandfather has a profound mistrust of anything new or foreign.There was a note of profound irritation in his voice.Strong feelingsVery and extremeComplete and wholeIntensifying expressions