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English definition of “screw sb up”

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screw sb up

informal
verb uk phrasal verb with screw   /skruː/ us  
When bad experiences or people screw you up, they make you worried and unhappy or damage your personality: It really screwed him up when he saw his friend get killed.
(Definition of screw sb up from the Cambridge Advanced Learners Dictionary & Thesaurus © Cambridge University Press)
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