›to separate something or someone from other things or people with which they are joined are mixed, or to keep them separate: We need to isolate the problem with our product distribution.
›POLITICSto keep a company or country from doing business in the usual way: Despite American efforts to isolate the country, Europeans still travel and trade there freely.isolate sb/yourself from sthThere is no way you can isolate yourself from politics unless you isolate yourself from society.