›very large, important, or powerful, especially when compared with others of the same type: a rail link connecting major European citiesExports play a major role in key sub-sectors.Our prices are lower on 2,000 items than those of all our major competitors.major companies/corporations/retailers
›a major change, difference, etc. affects a lot of people or organizations, sometimes in a way that causes difficulties for them: Lack of skilled workers has become a major problem in recent years.Governments now face major challenges in addressing problems in the global economy.a major barrier/obstacle/boost