Meaning of “lead off (something)” in the English Dictionary

american-english dictionary

"lead off (something)" in American English

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lead off (something)

phrasal verb with lead us /lid/ verb past tense and past participle led /led/

to be the first of a series of people to do something:

"Who’s the first speaker in the sales conference?" "Sally is leading off."
The 1998 expedition led off a series of annual ocean experiments.

(Definition of “lead off (something)” from the Cambridge Academic Content Dictionary © Cambridge University Press)