monoclonal gammopathy of unknown significance Meaning in the Cambridge English Dictionary Cambridge dictionaries logo

Meaning of “monoclonal gammopathy of unknown significance” in the English Dictionary

"monoclonal gammopathy of unknown significance" in British English

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monoclonal gammopathy of unknown significancenoun [U]

uk   /mɒn.əˌkləʊ.nəl ɡæmˌɒp.ə.θi əv ʌn.nəʊn sɪɡˈnɪf.ɪ.kənts/  us   /ˌmɑn.əˈkloʊ.nəl ɡæˈmɑp.ə.θi əv ˈʌnˌnoʊn sɪɡˈnɪf.ɪ.kəns/ (abbreviation MGUS, benign monoclonal gammopathy, monoclonal gammopathy of undetermined significance) specialized
a ​condition in which the ​bodyproduces high ​levels of an ​abnormalproteinfound in the ​blood, called paraprotein. The ​condition does not usually ​cause any ​symptoms but in a few ​cases may ​lead to the ​development of ​multiple myeloma (= ​cancer in the ​plasmacells in ​bonemarrow).
(Definition of monoclonal gammopathy of unknown significance from the Cambridge Advanced Learner’s Dictionary & Thesaurus © Cambridge University Press)
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