of course Meaning in the Cambridge English Dictionary
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Meaning of “of course” in the English Dictionary

"of course" in British English

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of course

A1 informal used to say yes or to give someone ​permission to do something: "Can you ​help me?" "Of course." "May I ​look at ​yournewspaper?" "Of course you can." "Have you written ​yourEnglishessayyet?" "Of course, I ​finished it last ​week." B1 used to show that what you are saying is ​obvious or already ​known: The Second World War ​ended, of course, in 1945. used to show that a ​situation or a ​piece of ​information is not ​surprising: We ​arrived at the ​restaurant 30 ​minutes late so, of course, ​ourreservation had been ​cancelled.
(Definition of of course from the Cambridge Advanced Learner’s Dictionary & Thesaurus © Cambridge University Press)

"of course" in American English

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of course

yes, ​certainly: "May I use ​yourtelephone?" "Of course, go ​rightahead."
(Definition of of course from the Cambridge Academic Content Dictionary © Cambridge University Press)
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