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Meaning of “systemic” in the English Dictionary

"systemic" in British English

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systemicadjective

uk   /sɪˈstem.ɪk/  us   /sɪˈstem.ɪk/
specialized biology A systemic drug, disease, or poison reaches and has an effect on the whole of a body or a plant and not just one part of it.
formal A systemic problem or change is a basic one, experienced by the whole of an organization or a country and not just particular parts of it: The current recession is the result of a systemic change within the structure of the country's economy.
(Definition of systemic from the Cambridge Advanced Learner’s Dictionary & Thesaurus © Cambridge University Press)

"systemic" in American English

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systemicadjective

 us   /sɪˈstem·ɪk/
relating to or involving a whole system: The problems are systemic and will only worsen.
(Definition of systemic from the Cambridge Academic Content Dictionary © Cambridge University Press)

"systemic" in Business English

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systemicadjective

uk   us   /sɪˈstemɪk/
relating to or affecting the whole of a system, organization, etc. rather than just some parts of it: These problems, far from being transitory, are systemic. The evidence suggests systemic failures on the part of the company's managers. We need a systemic change.
(Definition of systemic from the Cambridge Business English Dictionary © Cambridge University Press)
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