Meaning of “take it out of sb” in the English Dictionary

british dictionary

"take it out of sb" in British English

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take it out of sb

also take a lot out of sb
phrasal verb with take uk /teɪk/ us /teɪk/ verb took, taken

to make someone very tired:

Running around after 25 preschoolers takes it out of me by the end of the week.

(Definition of “take it out of sb” from the Cambridge Advanced Learner’s Dictionary & Thesaurus © Cambridge University Press)