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English definition of “vicissitudes”

vicissitudes

noun [plural]     /vɪˈsɪs.ɪ.tjuːdz/ US  /-tuːdz/ formal
changes that happen at different times during the life or development of someone or something, especially those that result in conditions being worse : Losing your job is just one of the vicissitudes of life .Change and changes
(Definition of vicissitudes noun from the Cambridge Advanced Learner's Dictionary & Thesaurus © Cambridge University Press)
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