anti-federalistadjective
uk /ˌæn.tiˈfed.ər.əl.ist/ us /ˌæn.t̬iˈfed.ɚ.əl.ist/ UK also mainly US anti-federal› opposed to a federalist system of government (= one in which power is divided between a central government and several local ones):
The Foreign Secretary assured anti-federalist MPs that he would not agree to anything that limited British sovereignty.