Definition of “systemic” - English Dictionary

“systemic” in English

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uk /sɪˈstem.ɪk/ us /sɪˈstem.ɪk/

specialized biology A systemic drug, disease, or poison reaches and has an effect on the whole of a body or a plant and not just one part of it.

formal A systemic problem or change is a basic one, experienced by the whole of an organization or a country and not just particular parts of it:

The current recession is the result of a systemic change within the structure of the country's economy.

(Definition of “systemic” from the Cambridge Advanced Learner's Dictionary & Thesaurus © Cambridge University Press)

“systemic” in American English

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us /sɪˈstem·ɪk/

relating to or involving a whole system:

The problems are systemic and will only worsen.

(Definition of “systemic” from the Cambridge Academic Content Dictionary © Cambridge University Press)

“systemic” in Business English

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uk /sɪˈstemɪk/ us

relating to or affecting the whole of a system, organization, etc. rather than just some parts of it:

These problems, far from being transitory, are systemic.
The evidence suggests systemic failures on the part of the company's managers.
We need a systemic change.

(Definition of “systemic” from the Cambridge Business English Dictionary © Cambridge University Press)