Meaning of “strike out” - Learner’s Dictionary

strike out

phrasal verb with strike us uk /straɪk/ verb past tense and past participle struck

to start moving towards somewhere in a determined way:

She struck out for the opposite bank.
FAIL US informal

to fail at something:

I really struck out with her - she wouldn't even let me kiss her goodbye.

(Definition of “strike out” from the Cambridge Learner’s Dictionary © Cambridge University Press)